By Arno Muller
What is AMC tool?
AMC Tool is the successor of ABC Calc and it is a simple computer tool to measure antimicrobial consumption in both hospital and community healthcare sectors. It transforms aggregated data provided as a number of packages or vials into meaningful antimicrobial utilisation rates.
The development of AMC Tool has been partly supported by the European Centre for Disease Prevention and Control (ECDC) under the framework contract ECDC/2012/042.
What is new?
AMC Tool computes antimicrobial consumption using the Anatomical Therapeutic Chemical (ATC) classification and the Defined Daily doses (DDD) of the ATC/DDD system developed by the WHO Collaborating Centre for Drug Statistics Methodology, Oslo Norway. AMC Tool is a completely new programme developed from scratch. It is made available under an open source licence (GPL) and is multi-platform.
The objectives of AMC Tool as compared with ABC calc are:
- to improve the user experience
- to improve the maintainability in terms of development.
Compared to ABC Calc, AMC Tool has some additional functionalities:
- AMC Tool can process other antimicrobials classes than antibiotics such as antimycotics, antivirals.
- The possibility to use two different indicators (DDD per 100 bed-days and DDD per 1000 inhabitants per day) as denominator makes AMC Tool useful for measuring antimicrobial consumption in hospitals but also in the community.
How to get AMC Tool?
AMC Tool can be downloaded here. A Windows® automatic install programme is provided for ease of use. To support users, a manual has been developed and is also available on the website.
What does AMC Tool report?
As recommended by WHO, AMC Tool reports hospital antimicrobial consumption as a number of DDD per 100 bed-days and community antimicrobial consumption as a number of DDD per 1000 inhabitants per day. For a specific drug, the DDD corresponds to the assumed average daily dose for its main indication in adults. DDDs are assigned by the WHO Collaborating Centre for Drug Statistics Methodology and updated once a year. AMC Tool is updated every year to use the latest version of the ATC/DDD index.
What does AMC Tool cover?
At present, AMC Tool deals with mostly antimicrobials for systemic use that covers the groups J01 (Antibacterials for systemic use), J02 (Antimycotics for systemic use), J04 (Antimycobacterials) and J05 (Antivirals for systemic use) of the ATC classification system. Other ATC groups relevant for antimicrobial consumption such as A07AA (Intestinal antiinfectives, incl. for selective decontamination of the digestive tract), D01BA (Antifungals for systemic use) and P01A (Agents against amoebiasis and other protozoal diseases) are also covered. Antibacterials for topical use, which are found in other ATC groups, are excluded.
“Promotion of the collection of data on antimicrobial consumption, and increase of awareness about antimicrobial misuse are key factors to fight against antimicrobial resistance worldwide.”
These are some screenshots of key steps of AMC Tool in use:
1. ATC/DDD index information panel
2. Data entry. Data entry panel with active auto-completion for the ATC substance field
3. DDD calculation. DDD calculation panel with bed-days denominator provided
4. Data import check. Automatic validation after import of data from a csv file.